Optimal dose of combined rocuronium and cisatracurium during minor surgery

Effects of Combined Rocuronium and Cisatracurium in Laparoscopic Cholecystectomy

BACKGROUND Laparoscopic upper abdominal surgery can cause spontaneous respiration due to diaphragmatic stimulation and intra-abdominal CO2 inflation. Therefore, sufficient muscle relaxation is necessary for a safe surgical environment. METHODS We investigated if the combination of rocuronium and cisatracurium can counteract the delayed onset of cisatracurium's action and delayed recovery of m...

Dose requirements of infusions of cisatracurium or rocuronium during hypothermic cardiopulmonary bypass.

We investigated the influence of mild hypothermic cardiopulmonary bypass (CPB) on the dose requirements of cisatracurium or rocuronium used as a continuous infusion. We studied eight patients given cisatracurium and nine given rocuronium. They were ASA class III and IV and scheduled for elective coronary artery bypass grafting. Neuromuscular transmission was monitored electromyographically. Aft...

Neuromuscular Block during Beating Heart Surgery, Comparison between Pancuronium, Rocuronium, and Cisatracurium

Priming with rocuronium to accelerate the onset time of cisatracurium during intubation.

BACKGROUND The priming technique, in which a small dose of nondepolarizing muscle relaxant is administered 3-6 minutes before giving the intubation dose, can speed up the onset of muscle relaxation in patients with paralysis during intubation. We investigated the priming technique and compared 2 different priming agents (rocuronium and cisatracurium) at a priming time of 3 minutes and its effec...

Cisatracurium in Cardiac Surgery

The aim of this study was the comparison of infusion vs. intermittent bolus administration of cisatracurium (CA) following cardiac surgery with regard to total intraoperative dose and time of recovery from neuromuscular blockade. From June 2005 to April 2006 sixty ASA II-III patients who were undergoing coronary bypass graft and valve replacement surgery, were equally divided and randomized to ...